Jalupro vs Profhilo: Clinical Comparison of Two Leading Skin Biorevitalisers
Introduction to Biorevitalisers
What Are Biorevitalisers?
Biorevitalisers are injectable treatments formulated to improve skin hydration, elasticity, and texture by encouraging natural regenerative processes within the skin. They differ from dermal fillers in that they work to enhance skin quality rather than change facial structure.
Benefits of Biorevitalisation for Skin Health
- Supports collagen and elastin production
- Delivers deep hydration
- Improves skin firmness and tone
- Enhances skin radiance in a natural way
Within the UK aesthetics sector, Jalupro Super Hydro and Profhilo are two well-established biorevitalising injectables valued for their clinical performance and patient satisfaction.
What is Jalupro Super Hydro?
Jalupro Super Hydro is an advanced injectable designed to promote skin regeneration, improve hydration, and support dermal restructuring. It builds upon the original Jalupro formula with a composition that includes additional active ingredients to address skin laxity.
Ingredients and Mechanism (Full List of Jalupro Super Hydro Ingredients)
- 80 mg of hybrid molecular weight hyaluronic acid
- Amino acids: Glycine, L-Proline, L-Leucine, L-Lysine
- Peptides: Acetyl Decapeptide-3, Tripeptide-1, Tripeptide-29
- Vitamin B6
- Sodium chloride and water for injection
This combination encourages fibroblast activity, supports collagen and elastin synthesis, and assists in dermal tissue restructuring.
How Do You Use Jalupro Super Hydro?
- Injection depth: Deep dermis or subcutaneous layer
- Protocol: Two sessions, spaced 3–4 weeks apart
- Treatment areas: Midface, cheeks, neck, décolletage, periocular area
Clinical Applications and Ideal Candidates
Suitable for individuals experiencing:
- Noticeable skin laxity
- Early signs of facial volume reduction
- Dehydrated or dull skin appearance
- Fine to moderate wrinkles
Does Jalupro Super Hydro Add Volume?
The product is not classified as a volumising filler, though its formulation can provide a mild lifting effect through skin bio-restructuring.
What is Profhilo?
Profhilo is a stabilised injectable hyaluronic acid product designed as a skin booster. It delivers hydration and supports dermal remodelling through a slow-release mechanism that promotes collagen and elastin production.
Ingredients and Mechanism (Full List of Profhilo Ingredients)
- 64 mg of pure hyaluronic acid (32 mg low molecular weight + 32 mg high molecular weight)
- Stabilised with NAHYCO® hybrid technology
- No chemical cross-linking agents
The formulation stimulates collagen and elastin production to improve skin firmness and hydration without altering facial volume.
How to Use Profhilo Facelift Treatment
- Injection depth: Subcutaneous layer, using the BAP (Bio Aesthetic Points) technique
- Protocol: Two sessions, spaced 4 weeks apart
- Treatment areas: Face, neck,
New Version of Profhilo: What You Need to Know
Profhilo Structura is a newer development aimed at deeper dermal layers for added structural support. It is intended for specific clinical applications where greater tissue integrity is required.
Is Profhilo a Filler or Skin Booster?
Profhilo is classed as a skin booster, not a dermal filler, as it is formulated to enhance skin quality rather than create volume or change facial shape.
Clinical Comparison

Efficacy and Longevity of Results
Both treatments aim to improve skin hydration, elasticity, and firmness.
- Jalupro Super Hydro incorporates amino acids and peptides in addition to hyaluronic acid, which contribute to dermal support.
- Profhilo contains a high concentration of pure hyaluronic acid and uses a stabilisation process to extend activity in the skin.
Clinical effects for both typically last 6–9 months, depending on individual skin condition, age, and lifestyle.
Differences in Treatment Protocols
| Feature | Jalupro Super Hydro | Profhilo |
| Sessions | 2 (3–4 weeks apart) | 2 (4 weeks apart) |
| Injection points | Customised for treatment area | 5-point BAP technique |
| Additional actives | Peptides, amino acids, vitamins | None |
| Volume change | Mild lifting effect | No volume change |
Patient Satisfaction and Observations
Feedback from clinics indicates positive results for both treatments. Patients report improvements in skin smoothness, hydration, and elasticity following treatment protocols.
Side Effects and Safety
Common Side Effects of Jalupro Super Hydro
- Mild redness or swelling
- Bruising at injection points
- Temporary tightness or itching
Common Side Effects of Profhilo
- Localised redness or swelling at injection sites
- Mild tenderness or bruising
- Temporary small nodules that resolve naturally
Contraindications and Precautions
- Pregnancy or breastfeeding
- Active skin infections
- Known sensitivity to hyaluronic acid or product components
- Autoimmune disorders without prior specialist consultation
Pricing and Availability
How Much Does Jalupro Super Hydro Cost to Buy?
- Approximate wholesale cost: £80–£110 per vial
- Available to Aesthetic Professionals
- Buy Jalupro now
How Much Is Profhilo for Clinics?
- Approximate wholesale cost: £90–£120 per 2 ml
- Buy Profhilo now
Where to Buy These Products
Both products are available via Skin On You
Conclusion
Which Biorevitaliser Should You Choose?
The decision between Jalupro Super Hydro and Profhilo depends on treatment objectives and patient needs. Factors such as desired active ingredients, protocol preferences, and specific skin concerns should guide selection.
Final Recommendations for Clinics
Jalupro Super Hydro and Profhilo each offer clinically proven benefits for skin quality improvement. Adding one or both to your treatment menu can expand options for patients seeking non-surgical skin rejuvenation.
Buy Jalupro now or Buy Profhilo now from Skin On You to access verified products for professional use.
