Description
Clinical Description
ILLUMA PN PRO (2%) 2 × 2.5ml Lidocaine is a professional polynucleotide (PN) skin booster developed for aesthetic medicine to support skin revitalisation and tissue quality improvement. Formulated with highly purified polynucleotides (2%) and lidocaine for improved patient comfort during administration, the product is intended to help improve skin hydration, elasticity, and overall dermal appearance through regenerative aesthetic treatment protocols.
Polynucleotides are highly purified DNA fragments that provide a supportive extracellular environment and are widely used in regenerative aesthetic medicine to promote tissue repair mechanisms and improve skin quality. Unlike cross-linked dermal fillers that primarily restore volume, ILLUMA PN PRO is designed as a biostimulatory skin booster focused on improving skin condition rather than volumisation.
The product is supplied in sterile prefilled syringes for use only by qualified medical professionals under appropriate aseptic conditions.
What ILLUMA PN PRO Is Similar To
ILLUMA PN PRO belongs to the growing category of regenerative injectable skin boosters based on purified polynucleotides. It may be compared with products such as PhilArt®, Plinest®, and Nucleofill®, all of which utilise polynucleotide technology to support skin quality improvement rather than providing volumising correction.
Unlike hyaluronic acid skin boosters such as Profhilo®, which primarily improve hydration through stabilised hyaluronic acid, ILLUMA PN PRO uses purified polynucleotides intended to support dermal regeneration and tissue repair mechanisms.
Although these products share the common objective of improving skin quality, they differ in formulation, concentration, manufacturing technology, and recommended treatment protocols. Product selection should therefore be based on clinical assessment, patient suitability, and manufacturer guidance.
This comparison is provided for clinical orientation only and does not imply interchangeability.
Treatment Areas / Indications
Publicly available manufacturer and distributor information indicates suitability for skin quality improvement in areas including:
- Face
- Neck
- Décolletage
- Hands
Usage / Administration (IFU-Only Section)
Administration: Intradermal injection by qualified healthcare professionals.
Professional-use statement: Administer only by qualified medical professionals using appropriate aseptic techniques.
Some practitioners describe specific polynucleotide injection protocols in educational literature; however, these methods are not included in the manufacturer’s official IFU guidance.
Ingredient List
Active ingredients:
- Purified Polynucleotides (PN) – 2%
- Lidocaine (concentration not publicly specified by manufacturer)
Other components:
- Physiological buffer solution
- Sterile water for injection
Presentation & Longevity
Presentation
- 2 × 2.5ml sterile prefilled syringes
- Sterile single-use presentation
Shelf Life
Not provided by manufacturer in publicly available documentation.
Longevity
Treatment duration is not provided by manufacturer. Clinical longevity may vary depending on patient characteristics, treatment protocol, and practitioner assessment.
Safety Notes / Contraindications
Manufacturer information recommends that treatment be performed only by qualified healthcare professionals.
Contraindications and precautions include:
- Do not inject into areas with active skin infection or inflammation.
- Use caution in patients with autoimmune disorders or impaired wound healing where clinically appropriate.
- Do not use if sterile packaging has been damaged.
Where complete contraindication information is unavailable publicly, practitioners should consult the manufacturer’s IFU before treatment.
Regulatory Status
Manufacturer documentation identifies ILLUMA PN PRO as a professional-use medical aesthetic injectable.
- CE Marking: Verify via manufacturer documentation and product packaging.
- UK Regulatory Status: Verify through authorised UK distributor.
- FDA Status: Not specified in publicly available documentation.
- Regulatory classification: Regulatory classification not specified in public documentation; verify on the product pack or manufacturer’s IFU.
FAQ
1. What is ILLUMA PN PRO?
ILLUMA PN PRO is a professional injectable skin booster formulated with purified polynucleotides (2%) and lidocaine. It is intended to support improvements in skin quality through regenerative aesthetic treatment protocols rather than by restoring facial volume. The product is designed for use only by appropriately trained healthcare professionals.
2. How does ILLUMA PN PRO differ from hyaluronic acid skin boosters?
Unlike hyaluronic acid skin boosters that primarily improve hydration through HA, ILLUMA PN PRO contains purified polynucleotides intended to support tissue regeneration and dermal quality. Both categories aim to improve skin appearance but use different biological mechanisms and formulations.
3. Does ILLUMA PN PRO contain lidocaine?
Yes. ILLUMA PN PRO contains lidocaine to improve patient comfort during treatment. However, the exact lidocaine concentration is not specified within publicly available manufacturer documentation and should be confirmed via the official IFU.
4. How is ILLUMA PN PRO administered?
Manufacturer information confirms intradermal administration by qualified healthcare professionals. Publicly available documentation does not specify injection depth, injection volume, needle gauge, or treatment frequency; therefore these parameters should be verified using the official manufacturer Instructions for Use.
5. What products are similar to ILLUMA PN PRO?
ILLUMA PN PRO belongs to the same regenerative injectable category as products including PhilArt®, Plinest®, and Nucleofill®. While these products all utilise polynucleotide technology, differences exist in concentration, purification processes, formulation, and manufacturer-recommended treatment protocols. They should not be considered interchangeable without clinical assessment.




