Description
Clinical Description
Nucleofill Hair – Nucleofill Medium Plus 1 x 2 ml is a professional-use polynucleotide-based biostimulating treatment developed by Promoitalia for scalp revitalisation and hair-support protocols. The product belongs to the Nucleofill regenerative medicine range and contains highly purified polynucleotides designed to support tissue quality through hydration, antioxidant activity, and biological stimulation of scalp tissues.
Polynucleotides are naturally derived DNA fragments with a high affinity for water molecules. Within aesthetic medicine, they are used to create a favourable environment for cellular activity and extracellular matrix support. Nucleofill Hair is specifically marketed for use in scalp rejuvenation programmes where patients present with signs of hair thinning, reduced hair density, or scalp ageing.
Unlike conventional hair-loss medications, Nucleofill Medium Plus is positioned as a regenerative injectable treatment intended to support scalp quality and tissue health rather than functioning as a pharmaceutical therapy.
Short Marketing Description
Nucleofill Hair – Nucleofill Medium Plus is a specialised polynucleotide treatment developed for scalp revitalisation and hair-support procedures. The formulation combines purified polynucleotides with a professional treatment approach aimed at improving the biological environment of the scalp.
The product is commonly incorporated into aesthetic hair-restoration protocols where practitioners seek to support hydration, tissue regeneration, and overall scalp quality. Its regenerative mechanism differs from traditional dermal fillers because it focuses on biological stimulation rather than volume enhancement.
Clinics offering advanced regenerative aesthetic treatments frequently use Nucleofill Hair as part of comprehensive scalp and hair-care programmes.
What Nucleofill Hair Is Similar To
Nucleofill Hair belongs to the expanding category of polynucleotide-based regenerative injectables. It is often compared with products such as Plinest Hair®, Newest®, and other polynucleotide scalp treatments that utilise purified nucleic acid fragments to support scalp revitalisation.
Compared with standard Nucleofill Medium facial formulations, Nucleofill Hair is specifically positioned for scalp applications and hair-support protocols.[1] Both products utilise polynucleotides as their primary active ingredient, but their intended treatment areas differ.
Nucleofill Hair may also be compared with platelet-rich plasma (PRP) procedures because both approaches aim to improve the biological environment of scalp tissues. However, PRP is derived from autologous blood products, whereas Nucleofill Hair uses purified polynucleotide technology manufactured under controlled production processes.
This comparison is provided for clinical orientation only and does not imply interchangeability.
Treatment Areas / Indications
According to publicly available manufacturer and distributor information, treatment areas include:
- Scalp
- Hair-bearing scalp regions
- Areas affected by reduced hair density
- Areas showing signs of scalp ageing
- Hair revitalisation protocols
- Hair-support treatment programmes
Usage / Administration (IFU-Only Section)
Injection depth: Not provided by manufacturer in publicly accessible IFU documentation reviewed.
Volume per injection site: Not provided by manufacturer.
Needle gauge: Not provided by manufacturer.
Treatment frequency / number of sessions: Not provided by manufacturer.
Professional-use statement: The product should be administered only by appropriately trained healthcare professionals using aseptic techniques and in accordance with local regulations.[1]
Some practitioners incorporate Nucleofill Hair into multi-session scalp treatment programmes; however, specific protocols were not verified in the manufacturer’s publicly available IFU and therefore are not reproduced here.
Ingredient List
Active Ingredients
- Highly purified polynucleotides (PN)
- Polynucleotide concentration reported in distributor documentation as approximately 20 mg/ml
Excipients
- Physiological saline solution (where specified by distributor documentation)
Hyaluronic Acid Content
- Not provided by manufacturer
Lidocaine Content
- Not provided by manufacturer
Presentation & Longevity
Presentation
- 1 × 2 ml sterile prefilled syringe
- Single-use professional medical-aesthetic product
- Intended for administration by qualified healthcare practitioners
Clinical outcomes and duration may vary depending on individual patient characteristics, scalp condition, practitioner protocol, and maintenance schedules.
Safety Notes / Contraindications
A complete contraindication list was not identified in publicly accessible documentation reviewed for this description.
General precautions include:
- Do not use in patients with known hypersensitivity to product components.
- Avoid treatment in areas affected by active infection, inflammation, or dermatological disease.
- Use only by qualified healthcare professionals.
- Clinical assessment should be performed before treatment in patients with significant medical conditions.
Refer to the latest manufacturer instructions and product packaging before clinical use.
Regulatory Status
- Manufacturer: Promoitalia Group (Italy)
- CE-marked product reported by authorised European distributors.
- Distributed within European medical-aesthetic markets.
Verify regulatory classification and market authorisation using the latest manufacturer documentation, product packaging, and local regulatory requirements prior to purchase or use.
FAQ
1. What is Nucleofill Hair – Nucleofill Medium Plus?
Nucleofill Hair is a polynucleotide-based injectable developed for scalp revitalisation and hair-support procedures. It contains purified polynucleotides designed to support hydration and biological activity within scalp tissues. The product is commonly used as part of regenerative aesthetic treatment programmes targeting scalp quality and hair-support goals.
2. How does Nucleofill Hair work?
Polynucleotides possess water-binding and tissue-supporting properties. Within aesthetic medicine, they are used to create a favourable environment for cellular activity and tissue regeneration. Nucleofill Hair is designed to support scalp quality through regenerative mechanisms rather than by adding volume or acting as a pharmaceutical hair-loss treatment.
3. Is Nucleofill Hair the same as a dermal filler?
No. Nucleofill Hair is generally categorised as a biostimulating polynucleotide treatment rather than a volumising dermal filler. Traditional fillers are typically intended to restore volume and contour, whereas Nucleofill Hair is positioned as a regenerative treatment for scalp and tissue-quality support.
4. What treatment areas is Nucleofill Hair intended for?
Publicly available product information associates Nucleofill Hair with scalp revitalisation and hair-support treatment programmes. It is typically selected by practitioners seeking regenerative treatment options for patients experiencing reduced hair density or scalp ageing concerns.
5. How long do the effects of Nucleofill Hair last?
The manufacturer does not provide a universally applicable longevity claim within publicly available documentation reviewed for this description. Treatment outcomes depend on patient-specific factors, practitioner protocols, treatment objectives, and maintenance schedules. Patients should consult their practitioner regarding expected treatment timelines.
